An adverse drug reaction adr is an injury caused by taking medication adrs may occur following a single dose or prolonged administration of a drug or result from the combination of two or more drugs the meaning of this expression differs from the meaning of side effect as this last expression might also imply that the effects can be beneficial . The reaction can start soon after you take the medicine or up to 2 weeks after you stop an adverse drug reaction can cause serious conditions such toxic epidermal necrolysis ten and anaphylaxis ten can cause severe skin damage anaphylaxis is a sudden life threatening reaction that needs immediate treatment. Any drug that is capable of producing beneficial therapeutic effects can also cause unwanted adverse effects adverse drug reactions adrs are therefore common and constitute an important public health challenge in their own right. Studies show that the rate of adverse drug reactions increases exponentially in patients taking 4 or more medications 1 importantly some categories of drugs are especially at high risk for . Adverse drug reactions are usually classified as mild moderate severe or lethal see table classification of adverse drug reactions adrs severe or lethal adrs may be specifically mentioned in black box warnings in the physician prescribing information provided by the manufacturer
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